Yeah, same here. They're very different, and honesty is vital in this case; a guardian who's uncomfortable around disability would be terrible for the kids.
As far as the selfishness, I was hovering around "Brother is just mildly detached from family and isn't the sort to notice when people want actual or emotional support" until LW got to called my mother to ream her out for not telling him how serious their genetic condition was, as it affected his plans to have children with his wife one day at which point I wanted to smack him. Wanting family to share information about genetic conditions I am 1000000% in favor of, as you know. Caring enough to yell at your mom but not enough to call your sibling, though? You can fuck right off with that BS. That's what LW should ghost him for, not the guardianship.
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As far as the selfishness, I was hovering around "Brother is just mildly detached from family and isn't the sort to notice when people want actual or emotional support" until LW got to called my mother to ream her out for not telling him how serious their genetic condition was, as it affected his plans to have children with his wife one day at which point I wanted to smack him. Wanting family to share information about genetic conditions I am 1000000% in favor of, as you know. Caring enough to yell at your mom but not enough to call your sibling, though? You can fuck right off with that BS. That's what LW should ghost him for, not the guardianship.