Yeah, I have a friend who has a large and brightly-colored framed art print of a catgirl stripping for some catboys in her main sitting area, and it never even occurred to her until I pointed it out after she started using the space for a home business that some people who don't share her art tastes might find that uncomfortable. It's an expensive print by a well-known European artist she loved that was given to her as a gift, and she only ever thought of it as "Cool art!"

I can see how seeing a nude painting of someone you know might feel odd, but *she's* obviously ok with it - it's not like you're worried it's a violation of her consent that you're seeing it - and it's in her private home, where you were invited. Even if it was surprising at first, most people's eyes just glaze over art after the second or third time, and if you can't stop starting at it, that might be something you need to examine in yourself.